Empirical Health vs SiPhox Health
Empirical Health is cheaper to start ($190 vs $298 per year, lowest published plans). Empirical Health scores higher overall (8.6 vs 7.0).
By Julian Caraulani · prices checked
Quick verdict
Our pick between the two: Empirical Health
Empirical Health scores 8.6/10 against 7.0 for SiPhox Health, ahead on price and clinical care. SiPhox Health can still be the better fit: it is best for people who want to test at home on their own schedule and track change over time.
Side by side
| Empirical Health | SiPhox Health | |
|---|---|---|
| Lowest price | $190/yr (one-time payment) | $298/yr (per testing cycle; slowest cadence is every 6 months) |
| Our score | 8.6/10 | 7.0/10 |
| Treatments | Longevity memberships | At-home test kits, Hormone panels |
| Medication in price | Not stated | Not stated |
| Drugs dispensed | Not stated | Not stated |
| Labs | Not stated | Not stated |
| Membership | Not stated | Not stated |
| Insurance | No; self-pay | No; self-pay |
| States | Not confirmed: no state list found on its own site (2026-10-31) | 48 states (not HI, NY), per its own site (2026-10-31) |
| Cancellation | $190 panel is a one-time payment. Subscriptions auto-renew unless cancelled before period end by contacting Empirical; account closes at end of billing period. Refund policy for the panel not found. | Cancel, pause or modify anytime from the account portal; keep access to past data. |
| FDA warning letters | None found (October 31, 2026) | None found (October 31, 2026) |
| Trustpilot | 3.5/5 (3 reviews) | 4.7/5 (718 reviews) |
| Best for | Heart-focused testers who want ApoB and Lp(a) with a doctor-written report for one payment. | People who want to test at home on their own schedule and track change over time. |
| Prices checked | 2026-10-31 | 2026-10-31 |
Empirical Health: a closer look
Heart-focused panel of 100+ items at Quest or BioReference, with a physician-interpreted report. We searched the FDA warning-letter database on October 31, 2026 and found no letter naming Empirical Health.
In its favour
- One-time payment, no auto-renewing membership for the panel
- ApoB and Lp(a) included
- Publishes its NY and NJ price
To weigh
- Doctor video visit and care plan only in the $399 program; the $190 panel gets a physician-interpreted report.
- Biomarker count includes calculated ratios and risk scores.
- Medical services in 'over 30 states' with no published exclusion list.
- Only 3 Trustpilot reviews; little independent feedback.
SiPhox Health: a closer look
At-home upper-arm kits on a subscription, tested monthly, quarterly or twice a year. We searched the FDA warning-letter database on October 31, 2026 and found no letter naming SiPhox Health.
In its favour
- At-home upper-arm collection, no lab visit
- Cancel, pause or switch panels any time
- States CLIA and CAP accredited partner lab
To weigh
- Headline price excludes $25 shipping per cycle; $99 is first cycle only.
- Not available in New York or Hawaii.
- Privacy policy allows selling aggregated data and sharing de-identified data with AI vendors.
- Wellness-only service; outsourced lab, recurring subscription billed per cycle.
Which should you choose?
Choose Empirical Health
Best for heart-focused testers who want ApoB and Lp(a) with a doctor-written report for one payment. Its lowest all-in plan is $190/yr (one-time payment).
Check Empirical Health's priceChoose SiPhox Health
Best for people who want to test at home on their own schedule and track change over time. Its lowest all-in plan is $298/yr (per testing cycle; slowest cadence is every 6 months).
Check SiPhox Health's priceEmpirical Health vs SiPhox Health: questions people ask
Is Empirical Health or SiPhox Health cheaper?
Empirical Health starts lower at $190 per year versus $298 at SiPhox Health, comparing each program's lowest all-in plan.
Which is better, Empirical Health or SiPhox Health?
On our published score Empirical Health rates 8.6 and SiPhox Health rates 7.0. Empirical Health is best for heart-focused testers who want ApoB and Lp(a) with a doctor-written report for one payment; SiPhox Health is best for people who want to test at home on their own schedule and track change over time.
Do Empirical Health and SiPhox Health offer the same treatments?
Empirical Health: Longevity memberships. SiPhox Health: At-home test kits, Hormone panels.
Does either include the medication in the price?
Empirical Health: not stated. SiPhox Health: not stated.
Blood Test Watchdog compares testing services. It is not medical advice, does not interpret results and does not publish reference ranges as advice. Talk to a licensed clinician about which tests you need and what your results mean. Partner links may earn us a commission; our score never depends on it. Compare other programs.